PDD - NIMH-NCI Protein-Disease Database

PDD - NIMH-NCI Protein-Disease Database

NOTICE:
The PDD is no longer being maintained or updated and has been experiencing problems. It will be going off line in the near future. We suggest you visit the National Library of Medicine sites for PubMed and Medline for searching for information on proteins and diseases in which they are involved.

Papers describing the Protein Disease Database

  1. Merril CR, Goldstein MP, Myrick JE, Creed GJ, Lemkin PF. The protein disease database of human body fluids: I. Rationale for the development of this database. Appl Theor Electrophor. 1995;5(2):49-54. PMID: [PubMed - indexed for MEDLINE] PMID: 8573599 or (PDF)

  2. Lemkin PF, Orr GA, Goldstein MP, Creed GJ, Myrick JE, Merril CR (1995) The Protein Disease Database of human body fluids: II. Computer methods and data issues. Applied Theor Electrophoresis 5(2):55-72. PMID: 8573600 or (PDF)

Welcome to the Protein Disease Database (PDD) Working Database.

This server is part of the NIMH-NCI Protein-Disease Database project for correlating diseases with proteins observable in serum, CSF, urine and other common human body fluids based on biomedical literature.

The PDD is a relational database designed to answer questions regarding protein patterns found in common body fluids with respect to disease conditions discussed in the literature. Data is being collected and entered into the PDD relational database by collaborators. It may be searched in a variety of ways including looking for normalized protein concentration fold-changes of proteins (for disease states with respect to normal states) as well as other more complex queries.

The PDD may be accessed to: 1) find proteins by clicking on spots in a reference 2D gel map image, or 2) query the relational database. Query results are then shown as tables, graphs, 2D gel map images, or hypertext references to other WWW databases.

This interactive PDD software is used with the users browser to access the data in the relational database (both of which were developed by the Image Processing Section of the Laboratory of Experimental and Computational Biology, NCI/FCRDC).

More information of the PDD can be found here under General Documentation

Access to the PDD:
URL: http://www-lecb.ncifcrf.gov/PDD/
NCI Disclaimer
$Date: 1998/03/12 16:42:12 $ / Email: pdd@ncifcrf.gov
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