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The
Left Handed DNA
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- Tom Schneider |
version = 2.01 of leftyear1989.txt 2009 Sep 29
(Thanks to Linda Angeloff Sapienza, LASplumas@aol.com, for pointing this one out!)Hi there! Yes, I am a Newsweek reader. I am also an artist responsible for perhaps one of the first left-handed boo-boos.
My husband and his old advisor (Doolittle and Sapienza) wrote a piece on "Selfish DNA" that was accepted by Nature. Their paper and another by Crick and Orgel became the magazine's cover topic. Lucky me! I got to draw for Nature!
No one noticed that my design was left-handed until the journal was in press. I will admit that the scientists thought it was pretty funny (well, what could they do at that point?).
In the US the background color was an ugly light orange, but the British version was a vivid red.
I'm starting to feel like a real part of history here...uh, infamous too.
...
Thanks for a great site!
For the love of enzymes: the odyssey of a biochemist Cambridge, Mass., Harvard University Press, 1989.In the section on "Astonishing Machines of Replication" on page 227, figure 7-14 there is a figleaf covering the point of DNA replication, all of the strands coming out of it are left handed.
version = 2.01 of leftyear1995.txt 2009 Sep 29
@article{WatsonCrick1953,
author = "J. D. Watson
and F. H. C. Crick",
title = "Molecular Structure of Nucleic Acids:
A Structure for Deoxyribose Nucleic Acid",
journal = "Nature",
volume = "171",
pages = "737-738",
year = "1953"}
Bioinformatics & Genome Research: Proceedings of the Third International Florida State Conference Center, Tallahassee, Florida, 1-4 June 1994. World Scientific, Singapore. 981-02-2401-X publication date: Sept 1995On the cover there is a computer chip with both left and right handed DNA emerging from it.
version = 2.00 of leftyear1996.txt 2009 Sep 29
version = 2.00 of leftyear1997.txt 2009 Sep 29
version = 2.00 of leftyear1998.txt 2009 Sep 29
The New Creationism: Biology Under Attack
By Barbara Ehrenreich and Janet McIntosh
When social psychologist Phoebe Ellsworth took the podium at a recent
interdisciplinary seminar on emotions, she was already feeling rattled.
Colleagues who'd presented earlier had warned her that the crowd was
tough and had little patience for the reduction of human experience to
numbers or bold generalizations about emotions across cultures. Ellsworth
had a plan: She would pre-empt criticism by playing the critic, offering a
social history of psychological approaches to the topic. But no sooner had
the word "experiment" passed her lips than the hands shot up. Audience
members pointed out that the experimental method is the brainchild of
white Victorian males. Ellsworth agreed that white Victorian males had
done their share of damage in the world but noted that, nonetheless, their
efforts had led to the discovery of DNA. This short-lived dialogue
between paradigms ground to a halt with the retort: "You believe in DNA?"
http://www.thenation.com:80/issue/970609/0609ehre.htm
The Nation Digital Edition http://www.thenation.com
Copyright (c) 1997, The Nation Company, L.P. All rights reserved.
Electronic redistribution for nonprofit purposes is permitted, provided this
notice is attached in its entirety. Unauthorized, for-profit redistribution
is prohibited. For further information regarding reprinting and syndication,
please call The Nation at (212) 242-8400, ext. 226 or send e-mail to
Max Block at mblock@thenation.com.
version = 2.00 of leftyear1999.txt 2009 Sep 29
| Our Story So Far: The story line, if you have not had time to follow the previous 150 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ... |
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"TaKaRa offers an extensive and proven line of Molecular Biology Products" "Today's Research for Tomorrow's Revolution".
A full page ad with the upper half page occupied by colored displays of left-handed DNA. (Even more: The four bases are represented, presumably, by the colors green, red, yellow, and blue. Green is shown bonding with red; but red is also shown bonding with yellow; and yellow is also shown bonding with blue; and blue is also shown bonding with green. Looks like a revolution indeed!)."
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Iain D. Russell, Adam S. Grancell, and Peter K. Sorger,
J. Cell Biol.,
Volume 145, Number 5, June 1,
933-950,
(1999)
"The Unstable F-box
Protein p58-Ctf13 Forms
the Structural Core of the
CBF3 Kinetochore
Complex",
figure 10C,
reports that the centromere binding complex in
Saccharomyces cerevisiae
(yeast) is left handed.
This case was acknowledged by Peter Sorger and a corrected figure
will be printed.
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Reproduced from The Journal of Cell Biology, 1999, 145, 933-950 by copyright permission of the Rockefeller University Press |
"There is a DNA helix in the upper, outer corner of every one of the catalog's 28 pages. Except for the cover (page 1) which shows [two] right- handed DNAs, all the odd pages show left-handed DNA. The even pages show right-handed DNA. In addition, sprinkled throughout are little men in lab coats that partially cover skeletal [DNA] structures which are right- handed wherever the little man is holding a pointer in his left hand, and left-handed wherever the little man is holding a pointer in his right hand."I note also that the button on the man's lab coat switches sides depending on which hand holds the pointer. If I recall correctly, men's clothing (and the lab coats we have in the lab here) have the button on the right side when unclosed. This corresponds to the right handed DNA pictures. So we might infer that the original artist drew the image the "right" way, and it was flipped for publication. (Thanks to Jack Tessman, Emeritus Professor of Physics, Tufts University, Medford MA 02155, jack@silcon.com for pointing this one out!)
Science, August 6, 1999 [volume 285], p. 954, advertising membership in AAAS and subscription to Science, "Relied upon by 159,536 subscribers worldwide", shows one "spiral" (of what is presumably DNA) crossing UNDER the second "spiral" and then crossing back - again UNDER the second "spiral". But the representation improves as the little man scales to new heights.(Thanks to Jack Tessman, Emeritus Professor of Physics, Tufts University, Medford MA 02155, jack@silcon.com for pointing this one out!)
version = 1.45 of leftyear2000.txt 2009 Sep 29
| Our Story So Far: The story line, if you have not had time to follow the previous 235 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ... |
| "The striking symmetry of the X-ray crystallograph of DNA prepared by Rosalind Franklin was one of the last clues that led Watson and Crick to deduce the double-helical structure of DNA." |
Your literal translation is of course correct but the actual meaning is not "measure of man". The phrase "nach Mass" means "as you choose to have or design something". Perhaps a more appropriate way to translate the phrase would be "Artificial contructrion of Man".
"At last I have succeeded in changing our left-handed logo (see website). ... [They will have] a revised logo when we ran out of our current batch of letterhead paper. It was a very large batch. But hooray! - at last we have joined the ranks of the helically correct. "
I was intrigued by your 'Left Handed DNA Hall of Fame' and amused to see that the Wellcome Trust features by proxy: we are a co-funder of the Researchers in Residence initiative that features at number 72. However, things have moved on and the scheme is no longer run by the ASE and is now run by the Sheffield Hallam Department of Science Education, it also has a new logo. While I have no problem with you continuing to display the old logo along with the description, I'd appreciate it if you could put a note that the organisation running the scheme has changed and include a link to the new scheme (http://www.researchersinresidence.org), just in case one of our students is reading your page and is interested in getting involved.
Steve
Dr Steven Wooding - Partnerships Project Manager
The Wellcome Trust - http://www.wellcome.ac.uk
210 Euston Road, London NW1 2BE
Telephone: +44 (0)20 7611 8850
Fax: +44 (0)20 7611 8269
version = 1.99 of leftyear2001.txt 2009 Sep 29
| Our Story So Far: The story line, if you have not had time to follow the previous 331 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ... |
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| © American Scientist |
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| © TIBS 2001 |
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©
This artwork is copyrighted to Rubber Stamps of America |
"if this is truly the image which is on the stamp, then when the stamp is dipped in ink and stamped on a page it will reverse, making the DNA right handed."What an interesting point!!! The stamp itself would be correct! I corrected the link and then located it under "Things". The DNA is indeed shown as left handed in "Things". Then I checked out the "Messages" category and found that the messages can be read. This means that they are displaying what the stamp will print, not what's on the stamp itself. The stamp itself must be correct, but the images printed from it are reversed to be left handed ...
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